Yeah, it's a crap shoot, and...
This isn’t a straightforward case where removing the offending plugin will instantly confirm it as the source of the problem.
No, It could take hours or even all day to determine. You can't assume that because the issue seemingly stopped that you've found the cause. It is not that simple with a pooling issue.
If someone wants to try:
1. Remove a suspected plugin .cs file
2. Restart your server
3. Wait for the issue to return
4. If the issue returns, repeat with another plugin
5. Otherwise, continue waiting for no less than 12 hours.
6. If you skip a step, then you'll likely report the wrong plugin as the cause, and you'll know this when the issue returns again.
VERY frustrating.